Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506684 | 0.90 | CSNK2A1 (0.32) | KCNH2 | |
| SCHEMBL6509717 | 0.78 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL1558105 | 0.75 | ALDH1A1 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1552485 | 0.75 | ALDH1A1 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6500823 | 0.75 | KCNH2 (0.64) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8113361 | 0.74 | KDM4E (0.40) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1628321 | 0.74 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6532101 | 0.72 | KCNH2 (0.63) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1628646 | 0.71 | PIM3 (0.42) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1629770 | 0.70 | KDM4E (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |