Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MATK | P42679 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501496 | 0.90 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL6501206 | 0.77 | KCNH2 (0.31) | CSNK2A1CSNK2A2CSNK2BKCNH2MAPKAPK3 | |
| SCHEMBL6502697 | 0.73 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL6506826 | 0.72 | KCNH2 (0.35) | CSNK2A1CSNK2A2CSNK2BKCNH2 | |
| SCHEMBL6502846 | 0.70 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL6509717 | 0.68 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL6532101 | 0.66 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL1558105 | 0.64 | ALDH1A1 (0.37) | CSNK2A1CSNK2A2CSNK2BKCNH2MAPKAPK3 | |
| SCHEMBL1552485 | 0.64 | ALDH1A1 (0.37) | CSNK2A1CSNK2A2CSNK2BKCNH2MAPKAPK3 | |
| SCHEMBL8113361 | 0.63 | KDM4E (0.40) | KCNH2MAPKAPK3RPS6KB1MATKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |