Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487917 | 0.93 | PIK3C2B (0.39) | DHODHPIK3C2BSYKAGTR1AGTR2 | |
| SCHEMBL6498787 | 0.91 | BCL2 (0.40) | DCTPP1PIK3C2BNR4A2AGTR1AGTR2 | |
| SCHEMBL6488163 | 0.88 | PIK3C2B (0.37) | DCTPP1DHODHPIK3C2BNR4A2AGTR1 | |
| SCHEMBL6498230 | 0.87 | ALOX5AP (0.38) | DCTPP1NR4A2AGTR1AGTR2ALOX5AP | |
| SCHEMBL6492529 | 0.85 | PIK3C2B (0.38) | DCTPP1PIK3C2BALOX5APBCL2MCL1 | |
| SCHEMBL6496471 | 0.85 | DCTPP1 (0.37) | DCTPP1PIK3C2BALOX5APBCL2MCL1 | |
| SCHEMBL6498198 | 0.85 | DCTPP1 (0.47) | DCTPP1ALOX5APBCL2MCL1 | |
| SCHEMBL6501134 | 0.85 | BCL2 (0.47) | DHODHPIK3C2BBCL2MCL1 | |
| SCHEMBL6498346 | 0.83 | CD274 (0.37) | DCTPP1PIK3C2BALOX5APBCL2MCL1 | |
| SCHEMBL6488013 | 0.83 | BDKRB1 (0.36) | DCTPP1DHODHPIK3C2BAGTR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | GABRA1 966/4885GABRG2 1437/4885GABRB3 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.