Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6506109 | 0.99 | PDE5A (0.81) | PDE5A | |
| Sulfuric Acid SCHEMBL6506114 | 0.97 | PDE5A (0.79) | PDE5A | |
| SCHEMBL6510617 | 0.95 | PDE5A (0.75) | PDE5A | |
| SCHEMBL6508312 | 0.94 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6510228 | 0.94 | PDE5A (0.82) | PDE5A | |
| SCHEMBL6505526 | 0.94 | PDE5A (0.84) | PDE5A | |
| SCHEMBL6510171 | 0.94 | PDE5A (0.84) | PDE5A | |
| SCHEMBL6499870 | 0.93 | PDE5A (0.83) | PDE5A | |
| Hydrochloric Acid SCHEMBL6506209 | 0.93 | PDE5A (0.83) | PDE5A | |
| Sulfuric Acid SCHEMBL6499386 | 0.93 | PDE5A (0.82) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130983-A1 | Pyrrolopyrimidinone derivatives, process for preparation thereof, and method of using and composition comprising them | IN2GEN CO., LTD. (KR) | 2005-06-16 | — | — | US | claimed |
| EP-1362858-A1 | Pyrrolopyrimidinone derivates, process of preparation and use | SK Chemicals Co., Ltd. (KR) | 2003-11-19 | — | — | EP | claimed |
| US-20050130983-A1 | Pyrrolopyrimidinone derivatives, process for preparation thereof, and method of using and composition comprising them | IN2GEN CO., LTD. (KR) | 2005-06-16 | — | — | US | disclosed |
| EP-1362858-A1 | Pyrrolopyrimidinone derivates, process of preparation and use | SK Chemicals Co., Ltd. (KR) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130983-A1 | Pyrrolopyrimidinone derivatives, process for preparation thereof, and method of using and composition comprising them | DHPS, SDHA, FDPS | PDE5A 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.