Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495617 | 0.85 | MME (0.50) | PHGDH | |
| SCHEMBL6505823 | 0.84 | KMT2A (0.41) | PHGDH | |
| SCHEMBL6502012 | 0.83 | PIN1 (0.48) | PHGDHPIN1 | |
| SCHEMBL6503228 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL6503168 | 0.81 | KMT2A (0.39) | — | |
| SCHEMBL6505350 | 0.81 | PPARG (0.40) | — | |
| SCHEMBL6496485 | 0.80 | HSD17B10 (0.52) | — | |
| SCHEMBL6497349 | 0.79 | OPRK1 (0.40) | — | |
| SCHEMBL6494362 | 0.78 | NPY5R (0.43) | — | |
| SCHEMBL6496022 | 0.76 | PPARA (0.48) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |