Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362737 | 0.98 | PTGDR2 (0.45) | PTGDR2ALDH1A1ALOX15CYP2D6SLC6A2 | |
| SCHEMBL16654184 | 0.90 | ALDH1A1 (0.47) | PTGDR2ALDH1A1ALOX15CYP2D6SLC6A2 | |
| SCHEMBL341578 | 0.85 | PTGDR2 (0.50) | PTGDR2ALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28794360 | 0.85 | PTGDR2 (0.50) | PTGDR2ALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30730923 | 0.83 | PTGDR2 (0.53) | PTGDR2ALDH1A1ALOX15CYP2D6SLC6A2 | |
| SCHEMBL1702632 | 0.83 | PTGDR2 (0.49) | PTGDR2ALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL50486 | 0.83 | PTGDR2 (0.53) | PTGDR2ALDH1A1ALOX15CYP2D6SLC6A2 | |
| SCHEMBL4742961 | 0.82 | PTGDR2 (0.47) | PTGDR2ALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7882968 | 0.82 | ESR2 (0.44) | ALDH1A1ALOX15NPC1MEN1KMT2A | |
| SCHEMBL1515853 | 0.81 | PTGDR2 (0.47) | PTGDR2ALDH1A1ALOX15CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | PTGDR2 301/4885ALDH1A1 3345/4885ALOX15 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.