Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909093 | 0.83 | CA2 (0.56) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL27558460 | 0.82 | HTT (0.40) | ALDH1A1PTGS1LMNATSHRHTT | |
| SCHEMBL10978746 | 0.82 | CA2 (0.54) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL29248834 | 0.82 | CA2 (0.54) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| Hydrochloric Acid SCHEMBL2527629 | 0.82 | CA2 (0.54) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL27649243 | 0.81 | FFAR1 (0.55) | ALDH1A1HSD17B10CA2LMNAFFAR1 | |
| SCHEMBL11795064 | 0.80 | F2 (0.56) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL503594 | 0.80 | CA2 (0.52) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL1061942 | 0.80 | PTGS2 (0.67) | CA2CAMK2AAKR1B1PTGS1LMNA | |
| SCHEMBL29009922 | 0.80 | CA2 (0.52) | ALDH1A1HPGDHSD17B10CA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531269-A | \"inhibitors of nicotinamide phosphoribosyltransferase, compositions, products and uses thereof\ | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO | 2016-04-27 | — | — | CN | disclosed |
| CN-105431422-A | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-03-23 | — | — | CN | disclosed |
| CN-105121423-A | Novel 3- (4- (benzyloxy) phenyl) hex-4-ynoic acid derivative, method for preparing the same, and pharmaceutical composition for preventing and treating metabolic diseases comprising the same as an effective ingredient | HYUNDAI PHARM CO LTD | 2015-12-02 | — | — | CN | disclosed |
| CN-105073742-A | Flap modulators | JANSSEN PHARMACEUTICA NV | 2015-11-18 | — | — | CN | disclosed |
| CN-102666567-B | For the method and composition that the F-18 of the improvement of protein, peptide and other molecule marks | IMMUNOMEDICS, INC. (US) | 2015-08-26 | — | — | CN | disclosed |
| CN-104768932-A | Heteroaryl inhibitors of PDE4 | TETRA DISCOVERY PARTNERS LLC | 2015-07-08 | — | — | CN | disclosed |
| CN-104693193-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2015-06-10 | — | — | CN | disclosed |
| CN-102822165-B | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2015-02-25 | — | — | CN | disclosed |
| CN-103068799-B | Benzamide derivatives as HSP90 inhibitors and uses thereof | CHROMA THERAPEUTICS LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-101402562-B | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101284808-A | Compounds and methods for the inhibition of the expression of VCAM-1 | ATHEROGENICS INC (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-101282949-A | Azole and thiazole derivatives and their use | ARGENTA DISCOVERY LTD (GB) | 2008-10-08 | — | — | CN | disclosed |
| CN-101054345-A | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-10-17 | — | — | CN | disclosed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |
| CN-1886376-A | Pyridine compounds as dipeptidyl dipeptidase-IV inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| CN-1878786-A | Novel 17 beta-hydroxysteroid dehydrogenase type I inhibitors | SOLVAY PHARM GMBH (DE) | 2006-12-13 | — | — | CN | disclosed |
| CN-1602291-A | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-03-30 | — | — | CN | disclosed |
| WO-2005021496-A2 | SYNTHESIS OF DERIVATIVES OF GINKGOLIDE C | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-03-10 | — | — | WO | disclosed |
| CN-1263522-A | Compounds and methods for inhibiting VCAM-1 expression | ATHEROGENICS INC (US) | 2000-08-16 | — | — | CN | disclosed |
| CN-1202888-A | Isoquinoline derivatives and isoquinoline combinatorial libraries | TORREY PINES INST (US) | 1998-12-23 | — | — | CN | disclosed |