Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909093 | 0.83 | CA2 (0.56) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL11492108 | 0.82 | F2 (0.42) | CA2PTGS1LMNATSHRHTT | |
| SCHEMBL10922380 | 0.82 | HTT (0.40) | PTGS1LMNATSHRHTTPTGS2 | |
| SCHEMBL10978746 | 0.82 | CA2 (0.54) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2527629 | 0.82 | CA2 (0.54) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL29248834 | 0.82 | CA2 (0.54) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL1061942 | 0.80 | PTGS2 (0.67) | CA2CAMK2AAKR1B1PTGS1LMNA | |
| SCHEMBL11795064 | 0.80 | F2 (0.56) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL6502087 | 0.80 | ALDH1A1 (0.53) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL29009922 | 0.80 | CA2 (0.52) | CA2CAMK2AAKR1B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503714-A4 | LOW PROFILE COMBINATION DEVICE FOR GASTROSTOMY OR JEJUNOSTOMY APPLICATIONS HAVING ANTI-GRANULOMA FORMATION CHARACTERISTICS | PHILADELPHIA CHILDREN HOSPITAL (US) | 2007-01-24 | — | — | EP | claimed |
| US-20060078575-A1 | Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics | GOLDBERG ELIZABETH A | 2006-04-13 | — | — | US | claimed |
| US-6997909-B2 | Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2006-02-14 | — | — | US | claimed |
| EP-1503714-A2 | LOW PROFILE COMBINATION DEVICE FOR GASTROSTOMY OR JEJUNOSTOMY APPLICATIONS HAVING ANTI-GRANULOMA FORMATION CHARACTERISTICS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2005-02-09 | — | — | EP | claimed |
| US-20040024363-A1 | Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2004-02-05 | — | — | US | claimed |
| WO-2003088920-A2 | LOW PROFILE COMBINATION DEVICE FOR GASTROSTOMY OR JEJUNOSTOMY APPLICATIONS HAVING ANTI-GRANULOMA FORMATION CHARACTERISTICS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2003-10-30 | — | — | WO | claimed |
| US-20030099682-A1 | Apparatus and method for control of tissue/implant interactions | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-05-29 | — | — | US | claimed |
| US-6497729-B1 | SELF-ASSEMBLED BIOACTIVE POLYMER; PROSTHETICS; DRUG DELIVERY | THE UNIVERSITY OF CONNECTICUT | 2002-12-24 | — | — | US | claimed |
| EP-3190969-B1 | METHOD FOR THE MANUFACTURING OF COATED IMPLANTS | CELL AND MOLECULAR TISSUE ENG LLC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20200069409-A1 | Coated Surgical Mesh, and Corresponding Systems and Methods | Cell and Molecular Tissue Engineering, LLC | 2020-03-05 | — | — | US | disclosed |
| US-10405961-B2 | Coated surgical mesh, and corresponding systems and methods | Cell and Molecular Tissue Engineering, LLC (US) | 2019-09-10 | — | — | US | disclosed |
| US-10130288-B2 | Coated sensors, and corresponding systems and methods | Cell and Molecular Tissue Engineering, LLC (US) | 2018-11-20 | — | — | US | disclosed |
| US-9717583-B2 | Sensors, cannulas, collars and coated surgical mesh, and corresponding systems and methods | Cell and Molecular Tissue Engineering, LLC (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170143876-A1 | Coated Surgical Mesh, and Corresponding Systems and Methods | Cell and Molecular Tissue Engineering, LLC (US) | 2017-05-25 | — | — | US | disclosed |
| US-6997909-B2 | Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2006-02-14 | — | — | US | disclosed |
| EP-1503714-A2 | LOW PROFILE COMBINATION DEVICE FOR GASTROSTOMY OR JEJUNOSTOMY APPLICATIONS HAVING ANTI-GRANULOMA FORMATION CHARACTERISTICS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20040024363-A1 | Low profile combination device for gastrostomy or jejunostomy applications having anti-granuloma formation characteristics | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2004-02-05 | — | — | US | disclosed |
| WO-2003088920-A2 | LOW PROFILE COMBINATION DEVICE FOR GASTROSTOMY OR JEJUNOSTOMY APPLICATIONS HAVING ANTI-GRANULOMA FORMATION CHARACTERISTICS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2003-10-30 | — | — | WO | disclosed |
| US-20030099682-A1 | Apparatus and method for control of tissue/implant interactions | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-05-29 | — | — | US | disclosed |
| US-6497729-B1 | SELF-ASSEMBLED BIOACTIVE POLYMER; PROSTHETICS; DRUG DELIVERY | THE UNIVERSITY OF CONNECTICUT | 2002-12-24 | — | — | US | disclosed |