SCHEMBL6502170

SCHEMBL6502170

Cc1ccccc1S(=O)(=O)Nc1ncc(N)s1.Nc1cnc(NS(=O)(=O)c2ccccn2)s1.Nc1cnc(NS(=O)(=O)c2nccs2)s1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 5/20 0.38
SCN5A Q14524 5/20 0.38
SCN8A Q9UQD0 5/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.38
SLC40A1 Q9NP59 2/20 0.38
FBP1 P09467 1/20 0.37
KDM1A O60341 1/20 0.37
MAOA P21397 1/20 0.37
EDNRA P25101 3/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP2C9 P11712 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6506679 0.73 GAA (0.35) SCN1ASCN5ASCN8AALDH1A1KDM1A
SCHEMBL31311401 0.71 ALDH1A1 (0.56) SCN1ASCN5ASCN8AALDH1A1TDP1
SCHEMBL6508208 0.67 GAA (0.38) SCN1ASCN5ASCN8AALDH1A1TDP1
SCHEMBL29494648 0.65 ALDH1A1 (0.60) SCN1ASCN5ASCN8AALDH1A1TDP1
SCHEMBL1492421 0.65 ALDH1A1 (0.60) SCN1ASCN5ASCN8AALDH1A1TDP1
SCHEMBL6504893 0.65 CA1 (0.54) ALDH1A1TDP1EDNRALMNAKDM4E
SCHEMBL27853149 0.62 CA1 (0.66)
SCHEMBL13811756 0.61 KDM4E (0.50) ALDH1A1TDP1TP53SLC40A1MAOA
SCHEMBL7133049 0.61 SLC40A1 (0.45) SLC40A1EDNRAEDNRB
SCHEMBL1094208 0.60 SCN9A (0.61) SCN1ASCN5ASCN8AUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005014591-A1 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2005-02-17 WO disclosed