Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8069043 | 0.99 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1CYP26A1CFTR | |
| SCHEMBL8076680 | 0.97 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CYP26A1CFTR | |
| SCHEMBL6954487 | 0.83 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CYP26A1CFTR | |
| Bromide SCHEMBL11274115 | 0.75 | KCNA5 (0.41) | CYP11B1CYP11B2CYP19A1CFTRSLC6A2 | |
| SCHEMBL6505968 | 0.75 | CYP3A4 (0.49) | CYP11B1CYP11B2CYP19A1CFTRSLC6A2 | |
| SCHEMBL360712 | 0.75 | CFTR (0.57) | CYP11B1CYP11B2CYP19A1CFTRSLC6A2 | |
| SCHEMBL6501170 | 0.74 | CYP19A1 (0.46) | CYP11B1CYP19A1CFTRSLC6A2SLC6A4 | |
| SCHEMBL3903975 | 0.74 | CYP11B1 (0.44) | CYP11B1CYP19A1CFTRSLC6A2SLC6A4 | |
| SCHEMBL6503338 | 0.73 | CYP19A1 (0.62) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6502611 | 0.73 | POLB (0.51) | CYP11B1CYP11B2CYP19A1CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-0149884-A2 | 5-Pyridyl-1,3-thiazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | CYP11B1 2166/4885CYP11B2 2363/4885CYP19A1 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.