SCHEMBL6502474

SCHEMBL6502474

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(SC(F)(F)F)c(F)c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
USP2 O75604 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
PPIA P62937 2/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
PKM P14618 2/20 0.38
HTT P42858 3/20 0.36
JAK2 O60674 1/20 0.36
JAK1 P23458 1/20 0.36
TYK2 P29597 1/20 0.36
NOD2 Q9HC29 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6504414 0.92 KMT2A (0.52) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6505906 0.89 MEN1 (0.60) ATMMEN1KMT2AUSP2MAPT
SCHEMBL5316163 0.85 ATM (0.51) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6508055 0.85 MEN1 (0.55) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6505628 0.84 KMT2A (0.57) ATMMEN1KMT2AUSP2MAPT
SCHEMBL5310875 0.82 ATM (0.53) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6514583 0.82 MEN1 (0.52) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6509966 0.81 MEN1 (0.47) ATMMEN1KMT2AUSP2MAPT
SCHEMBL10646227 0.81 MEN1 (0.60) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6507096 0.80 KMT2A (0.52) ATMMEN1KMT2AUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 ATM 2564/4885MEN1 2593/4885KMT2A 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.