SCHEMBL6508055

SCHEMBL6508055

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(SC(F)(F)F)c(Cl)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
ATM Q13315 1/20 0.51
USP2 O75604 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47
PPIA P62937 3/20 0.38
NPC1 O15118 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
CXCR2 P25025 3/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
IL2 P60568 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6507096 0.94 KMT2A (0.52) MEN1KMT2AATMUSP2MAPT
SCHEMBL6505906 0.92 MEN1 (0.60) MEN1KMT2AATMUSP2MAPT
SCHEMBL6514583 0.90 MEN1 (0.52) MEN1KMT2AATMUSP2MAPT
SCHEMBL6505628 0.86 KMT2A (0.57) MEN1KMT2AATMUSP2MAPT
SCHEMBL6502474 0.85 ATM (0.53) MEN1KMT2AATMUSP2MAPT
SCHEMBL6507276 0.85 KMT2A (0.49) MEN1KMT2AATMUSP2MAPT
SCHEMBL5316163 0.83 ATM (0.51) MEN1KMT2AATMUSP2MAPT
SCHEMBL6504414 0.83 KMT2A (0.52) MEN1KMT2AATMUSP2MAPT
SCHEMBL6511572 0.82 KMT2A (0.60) MEN1KMT2AATMUSP2MAPT
SCHEMBL5310875 0.81 ATM (0.53) MEN1KMT2AATMUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 MEN1 2593/4885KMT2A 1362/4885ATM 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.