SCHEMBL5316163

SCHEMBL5316163

Cc1c(NC(=O)NC(=O)c2c(F)cccc2F)ccc(SC(F)(F)F)c1C

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.51
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
MAPT P10636 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39
PPIA P62937 2/20 0.38
PYGL P06737 1/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTGFR P43088 1/20 0.36
TRPA1 O75762 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514583 0.90 MEN1 (0.52) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6502474 0.85 ATM (0.53) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6507276 0.85 KMT2A (0.49) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6508055 0.83 MEN1 (0.55) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6509959 0.82 ATM (0.50) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6505906 0.82 MEN1 (0.60) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6509567 0.82 ATM (0.50) ATMMEN1KMT2AMAPTUSP2
SCHEMBL5310875 0.81 ATM (0.53) ATMMEN1KMT2AMAPTUSP2
SCHEMBL6503189 0.80 RAB9A (0.50) ATMMEN1KMT2AMAPTUSP2
SCHEMBL5311613 0.80 MEN1 (0.48) ATMMEN1KMT2AMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066496-A1 BENZOYLUREA COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 WO disclosed
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
WO-2005040112-A1 COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY OXAGEN LIMITED (GB) 2005-05-06 WO disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 ATM 2564/4885MEN1 2593/4885KMT2A 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.