Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502488 | 0.85 | ITGB3 (0.34) | ITGB3ITGAVALOX15CFDCTSK | |
| SCHEMBL14431790 | 0.84 | ITGB3 (0.40) | ITGB3ITGAVALOX15CTSK | |
| SCHEMBL6502492 | 0.75 | NPC1 (0.31) | CTSK | |
| SCHEMBL5206885 | 0.62 | ITGB3 (0.44) | ITGB3ITGAVCTSKBACE1 | |
| SCHEMBL14431256 | 0.62 | ITGB3 (0.44) | ITGB3ITGAVCTSKBACE1 | |
| SCHEMBL6495736 | 0.62 | ITGB3 (0.44) | ITGB3ITGAVALOX15CTSK | |
| SCHEMBL1209402 | 0.62 | ALOX15 (0.54) | ITGB3ITGAVALOX15 | |
| SCHEMBL1212529 | 0.59 | ALOX15 (0.40) | ITGB3ITGAVALOX15 | |
| SCHEMBL1211298 | 0.59 | ALOX15 (0.40) | ITGB3ITGAVALOX15CFD | |
| SCHEMBL10192477 | 0.59 | P2RX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849646-B1 | Chromenone and chromanone derivatives as integrin inhibitors | MERCK PATENT GMBH (DE) | 2005-02-01 | — | — | US | disclosed |