SCHEMBL650252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3692845	0.83	MAPT (0.46)	ALDH1A1KDM4ESMN1; SMN2HPGDNPC1
	SCHEMBL29265674	0.82	ALDH1A1 (0.53)	ALDH1A1KDM4ETSHRSMN1; SMN2HPGD
	SCHEMBL652110	0.82	KMT2A (0.45)	ALDH1A1TSHRSMN1; SMN2NPC1CA2
	SCHEMBL64028	0.81	NOTUM (0.49)	ALDH1A1KDM4ETSHRSMN1; SMN2HPGD
	SCHEMBL7831241	0.81	TSPO (0.49)	ALDH1A1TSHRSMN1; SMN2NPC1GAA
	SCHEMBL7830726	0.78	MEN1 (0.45)	ALDH1A1TSHRSMN1; SMN2RAB9AMEN1
	SCHEMBL8137983	0.77	TSHR (0.53)	ALDH1A1KDM4ETSHRSMN1; SMN2HPGD
	SCHEMBL15180119	0.77	ALDH1A1 (0.44)	ALDH1A1KDM4ETSHRSMN1; SMN2HPGD
	SCHEMBL2276155	0.77	MMP2 (0.45)	ALDH1A1TSHRGAATDP1RAB9A
	SCHEMBL3142097	0.77	PHLPP2 (0.46)	ALDH1A1TSHRSMN1; SMN2MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.