Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200156 | 0.88 | GRM5 (0.43) | FFAR1GRM5 | |
| SCHEMBL6198861 | 0.78 | GRM5 (0.44) | FFAR1GRM5 | |
| SCHEMBL6200767 | 0.76 | GRM5 (0.48) | GRM5 | |
| SCHEMBL6200432 | 0.75 | HPGD (0.44) | GRM5 | |
| SCHEMBL6198642 | 0.75 | GRM5 (0.50) | GRM5 | |
| SCHEMBL6207660 | 0.74 | GRM5 (0.43) | FFAR1GRM5 | |
| SCHEMBL8185025 | 0.72 | EGLN1 (0.40) | FFAR1GRM5 | |
| SCHEMBL8264835 | 0.72 | FFAR1 (0.57) | FFAR1GRM5 | |
| SCHEMBL8175574 | 0.70 | EGLN1 (0.38) | FFAR1GRM5 | |
| SCHEMBL6201462 | 0.69 | ADORA3 (0.47) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972299-B2 | Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles | HOFFMANN-LA ROCHE INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-20030208082-A1 | Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles | MUTEL VINCENT (FR) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208082-A1 | Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles | GRM5, GRIK5, GRM1 | FFAR1 450/4885GRM5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.