Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.37 |
| ▸ | FNTB | P49356 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175574 | 0.85 | EGLN1 (0.38) | EGLN1FNTAFNTBFFAR1LMNA | |
| SCHEMBL8186674 | 0.83 | PYGL (0.38) | FNTAFNTBALOX15LMNARIPK1 | |
| SCHEMBL8186684 | 0.82 | ACACB (0.38) | LMNA | |
| SCHEMBL8187914 | 0.82 | EGLN1 (0.36) | EGLN1FNTAFNTBFFAR1LMNA | |
| SCHEMBL8186495 | 0.80 | MAOB (0.36) | LMNA | |
| SCHEMBL8175327 | 0.80 | GRM4 (0.34) | LMNA | |
| SCHEMBL8185960 | 0.80 | RAB9A (0.40) | — | |
| SCHEMBL8184265 | 0.74 | EGLN1 (0.41) | EGLN1FFAR1GRM5CA12CA1 | |
| SCHEMBL8184417 | 0.74 | EGLN1 (0.41) | EGLN1FFAR1GRM5CA12CA1 | |
| SCHEMBL6502589 | 0.72 | FFAR1 (0.41) | FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077557-A1 | 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2008-07-03 | — | — | WO | disclosed |