Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250926 | 0.78 | — | — | |
| SCHEMBL9861722 | 0.76 | TSHR (0.46) | CYP2C19CA2CA12CA1CA7 | |
| SCHEMBL9861101 | 0.73 | TSHR (0.42) | CYP2D6ALDH1A1 | |
| SCHEMBL23829825 | 0.73 | — | — | |
| SCHEMBL9861435 | 0.72 | LMNA (0.44) | CYP2D6ALDH1A1 | |
| SCHEMBL9861780 | 0.70 | TSHR (0.46) | ALDH1A1 | |
| SCHEMBL9861404 | 0.70 | TSHR (0.46) | ALDH1A1 | |
| SCHEMBL9861163 | 0.70 | TSHR (0.46) | ALDH1A1 | |
| SCHEMBL16796104 | 0.69 | CYP2D6 (0.50) | CYP2D6CYP2C19HIF1APHGDHPOLB | |
| SCHEMBL1739737 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250957-A1 | Compounds containing thiosulfate moieties | MOLECULAR PROBES, INC | 2005-11-10 | — | — | US | disclosed |
| WO-2005047242-A2 | COMPOUNDS CONTAINING THIOSULFATE MOIETIES | MOLECULAR PROBES, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250957-A1 | Compounds containing thiosulfate moieties | TST, MPST, STS | CYP2D6 598/4885CYP2C19 1507/4885HIF1A 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.