Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490491 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL6488469 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL6487920 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL6489011 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL6499184 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL25272394 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL1285731 | 0.75 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6490529 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7829074 | 0.72 | NPC1 (0.56) | SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL18308295 | 0.72 | GAA (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | SMN1; SMN2 1128/4885ALDH1A1 96/4885MAOB 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.