Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489011 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL6490670 | 0.84 | HDAC1 (0.44) | SMN1; SMN2RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL28885280 | 0.80 | MAPT (0.61) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL6499184 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL977967 | 0.79 | MEN1 (0.66) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL6643446 | 0.78 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL5562070 | 0.77 | KMT2A (0.50) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL5563288 | 0.76 | MEN1 (0.50) | SMN1; SMN2RAB9ANPC1MAPTMAPK1 | |
| SCHEMBL4497487 | 0.76 | VCAM1 (0.55) | RAB9ANPC1MAPTMAPK1POLB | |
| SCHEMBL6704649 | 0.75 | MAPT (0.43) | SMN1; SMN2RAB9ANPC1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | SMN1; SMN2 1128/4885RAB9A 2599/4885NPC1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.