SCHEMBL6503189

SCHEMBL6503189

Cc1cc(NC(=O)NC(=O)c2c(F)cccc2F)ccc1SC(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.50
NPC1 O15118 7/20 0.50
PKM P14618 1/20 0.50
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
MAPT P10636 4/20 0.47
GAA P10253 2/20 0.47
KDM4E B2RXH2 2/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ATM Q13315 1/20 0.45
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
TP53 P04637 2/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6503010 0.92 GAA (0.51) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL6510220 0.89 RAB9A (0.50) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL6509959 0.84 ATM (0.50) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL6508233 0.82 TLR7 (0.50) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL11335679 0.82 TLR7 (0.50) RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL6509567 0.81 ATM (0.50) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL5316281 0.80 NPC1 (0.50) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL5316163 0.80 ATM (0.51) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL6508343 0.79 MEN1 (0.47) RAB9ANPC1PKMMEN1KMT2A
SCHEMBL15335266 0.79 RAB9A (0.64) RAB9ANPC1PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 RAB9A 1386/4885NPC1 2157/4885PKM 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.