Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507632 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2BRD4LMNAMAPK1RAB9A | |
| SCHEMBL17069079 | 0.80 | BRD4 (0.49) | SMN1; SMN2BRD4HDAC3HDAC6NCOR2 | |
| SCHEMBL6506932 | 0.77 | JAK2 (0.46) | SMN1; SMN2BRD4HDAC3HDAC6NCOR2 | |
| SCHEMBL17069072 | 0.75 | BRD4 (0.48) | SMN1; SMN2BRD4LMNAKDM4EMAPK1 | |
| SCHEMBL2488400 | 0.73 | MAPT (0.40) | HDAC3HDAC6NCOR2LMNAKDM4E | |
| SCHEMBL25587161 | 0.71 | HRH4 (0.41) | SMN1; SMN2PARP1LMNATTRHRH4 | |
| SCHEMBL3462652 | 0.71 | HDAC3 (0.44) | SMN1; SMN2BRD4HDAC3HDAC6NCOR2 | |
| SCHEMBL1040640 | 0.71 | HDAC3 (0.56) | SMN1; SMN2BRD4HDAC3HDAC6NCOR2 | |
| SCHEMBL22052743 | 0.70 | BRD4 (0.50) | SMN1; SMN2BRD4HDAC3HDAC6NCOR2 | |
| SCHEMBL26107873 | 0.70 | HDAC3 (0.65) | BRD4HDAC3HDAC6NCOR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1386915-A1 | AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | C1S, CYP4B1, CYP4X1 | SMN1; SMN2 4061/4885BRD4 3018/4885HDAC3 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.