Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507632 | 0.88 | SMN1; SMN2 (0.51) | JAK2SMN1; SMN2BRD4RAB9ANPC1 | |
| SCHEMBL17069076 | 0.80 | IDO1 (0.49) | SMN1; SMN2BRD4NR1H2NR1H3RAB9A | |
| SCHEMBL27498477 | 0.79 | NR1H2 (0.59) | SMN1; SMN2BRD4NR1H2NR1H3RAB9A | |
| SCHEMBL6503377 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2HDAC3HDAC6NCOR2BRD4 | |
| SCHEMBL17069075 | 0.75 | ADORA2A (0.50) | SMN1; SMN2BRD4NR1H2NR1H3RAB9A | |
| SCHEMBL3462652 | 0.71 | HDAC3 (0.44) | SMN1; SMN2HDAC3HDAC6NCOR2BRD4 | |
| SCHEMBL4859334 | 0.71 | NR1H2 (0.56) | HDAC3HDAC6NCOR2NR1H2NR1H3 | |
| SCHEMBL13545717 | 0.70 | NOTUM (0.52) | HDAC3HDAC6NCOR2RAB9ANPC1 | |
| SCHEMBL26107873 | 0.70 | HDAC3 (0.65) | HDAC3HDAC6NCOR2BRD4NR1H2 | |
| SCHEMBL1436121 | 0.69 | NR1H2 (0.61) | SMN1; SMN2HDAC3HDAC6NCOR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1386915-A1 | AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | C1S, CYP4B1, CYP4X1 | JAK2 4014/4885SMN1; SMN2 4061/4885HDAC3 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.