Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503377 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMAPK1BRD4NPC1 | |
| SCHEMBL6506932 | 0.88 | JAK2 (0.46) | SMN1; SMN2JAK2BRD4PIK3R2GAA | |
| SCHEMBL17069079 | 0.73 | BRD4 (0.49) | SMN1; SMN2LMNABRD4PIK3R2GAA | |
| SCHEMBL17069076 | 0.73 | IDO1 (0.49) | SMN1; SMN2BRD4PIK3R2NPC1RAB9A | |
| SCHEMBL6449933 | 0.73 | JAK2 (0.47) | SMN1; SMN2PTGESJAK2NPC1RAB9A | |
| SCHEMBL18938467 | 0.73 | LMNA (0.44) | SMN1; SMN2PTGESJAK2PDE2APDE10A | |
| SCHEMBL27498477 | 0.73 | NR1H2 (0.59) | SMN1; SMN2MAPK1BRD4GAANPC1 | |
| SCHEMBL14363623 | 0.72 | L3MBTL1 (0.50) | SMN1; SMN2LMNANPC1CASP3RAB9A | |
| SCHEMBL413486 | 0.72 | PTGES (0.43) | SMN1; SMN2PTGESJAK2PDE2APDE10A | |
| SCHEMBL22357751 | 0.71 | PDE2A (0.42) | SMN1; SMN2PTGESJAK2PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1386915-A1 | AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009834-A1 | Azole compounds, process for preparation of the same and use thereof | C1S, CYP4B1, CYP4X1 | SMN1; SMN2 4061/4885PTGES 4775/4885JAK2 4014/4885 |
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | SMN1; SMN2 4112/4885PTGES 94/4885JAK2 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.