Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 5/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655182 | 0.73 | L3MBTL1 (0.41) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9566587 | 0.73 | HRH4 (0.57) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL10203915 | 0.73 | RAB9A (0.44) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL15890878 | 0.73 | L3MBTL1 (0.41) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL18812086 | 0.72 | NPC1 (0.40) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL8372471 | 0.72 | TTR (0.41) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL20110472 | 0.71 | L3MBTL1 (0.50) | L3MBTL1ACHESMN1; SMN2 | |
| SCHEMBL20928241 | 0.71 | L3MBTL1 (0.50) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL19823579 | 0.71 | L3MBTL1 (0.50) | HRH4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL6503377 | 0.71 | SMN1; SMN2 (0.43) | HRH4NPC1RAB9ALMNATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11794180-B2 | Tri-(adamantyl)phosphines and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-20230158480-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | UNIV PRINCETON (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11794180-B2 | Tri-(adamantyl)phosphines and applications thereof | PADI3, ADA, ENTPD3 | HRH4 2032/4885L3MBTL1 4016/4885NPC1 4482/4885 |
| US-20230158480-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | PADI3, ADA, ENTPD3 | HRH4 2032/4885L3MBTL1 4016/4885NPC1 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.