Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296041 | 1.00 | PADI1 (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9961299 | 0.87 | CA14 (0.47) | PADI1PADI4POLBSMN1; SMN2CA14 | |
| SCHEMBL6495095 | 0.84 | KMT2A (0.39) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8297132 | 0.84 | KMT2A (0.39) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13033929 | 0.83 | TSHR (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL29789574 | 0.83 | TSHR (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3919225 | 0.82 | GABRP (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13113457 | 0.82 | GABRP (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8311892 | 0.82 | GABRP (0.47) | PADI1PADI4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13033925 | 0.80 | PADI1 (0.54) | PADI1PADI4POLBSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |