Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113457 | 1.00 | GABRP (0.47) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL3919225 | 1.00 | GABRP (0.47) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL844944 | 0.86 | RECQL (0.44) | POLBRAB9ARECQLSMN1; SMN2MEN1 | |
| SCHEMBL1952554 | 0.86 | RECQL (0.44) | POLBRAB9ARECQLSMN1; SMN2MEN1 | |
| SCHEMBL845078 | 0.86 | RECQL (0.44) | POLBRAB9ARECQLSMN1; SMN2MEN1 | |
| SCHEMBL4688805 | 0.82 | CHRNB2 (0.55) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL23441772 | 0.82 | RECQL (0.54) | TSHRPOLBRECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL10482801 | 0.82 | RECQL (0.54) | TSHRPOLBRECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL5901288 | 0.82 | RECQL (0.50) | POLBRECQLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6288389 | 0.82 | RECQL (0.50) | POLBRECQLSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043076-B1 | CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF | GENEFRONTIER CORP (JP) | 2024-06-26 | — | — | EP | disclosed |
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |