Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111413 | 0.89 | HRH1 (0.67) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL2971279 | 0.88 | HRH1 (0.46) | HRH1SLC6A4SLC6A2RIPK1SLC6A3 | |
| SCHEMBL11095478 | 0.85 | HRH1 (0.43) | HRH1SLC6A4SLC6A2RIPK1SLC6A3 | |
| SCHEMBL7315744 | 0.82 | HRH1 (0.44) | HRH1SLC6A4SLC6A2RIPK1SLC6A3 | |
| SCHEMBL29580562 | 0.81 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1SLC6A3 | |
| SCHEMBL7646958 | 0.81 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL6186762 | 0.81 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1SLC6A3 | |
| SCHEMBL2676995 | 0.81 | HRH1 (0.79) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL1070099 | 0.81 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL5389689 | 0.81 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | HRH1 1287/4885SLC6A4 1588/4885SLC6A2 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.