Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516631 | 0.93 | HRH1 (0.59) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL1067253 | 0.89 | HRH1 (0.67) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL17024100 | 0.88 | HRH1 (0.46) | HRH1RIPK1SLC6A4SLC6A2LTA4H | |
| SCHEMBL6503487 | 0.81 | HRH1 (0.62) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL5389689 | 0.81 | HRH1 (0.62) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL2676995 | 0.81 | HRH1 (0.79) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL6186762 | 0.81 | HRH1 (0.62) | HRH1RIPK1SLC6A4SLC6A2LTA4H | |
| SCHEMBL7646958 | 0.81 | HRH1 (0.62) | HRH1RIPK1SLC6A4SLC6A2FFAR1 | |
| SCHEMBL29580562 | 0.81 | HRH1 (0.62) | HRH1RIPK1SLC6A4SLC6A2LTA4H | |
| SCHEMBL194417 | 0.80 | HRH1 (0.60) | HRH1RIPK1SLC6A4SLC6A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838341-A | Organic compounds having soluble groups | 默克专利有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-3145935-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2017-03-29 | — | — | EP | disclosed |
| WO-2016188972-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | UNIVERSITEIT LEIDEN (NL) | 2016-12-01 | — | — | WO | disclosed |
| WO-2016188972-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | UNIVERSITEIT LEIDEN (NL) | 2016-12-01 | — | — | WO | disclosed |
| EP-3095787-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2016-11-23 | — | — | EP | disclosed |
| EP-3095787-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2016-11-23 | — | — | EP | disclosed |
| WO-2011003029-A2 | CATALYTIC DISPROPORTIONATION AND CATALYTIC REDUCTION OF CARBON-CARBON AND CARBON-OXYGEN BONDS OF LIGNIN AND OTHER ORGANIC SUBSTRATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-06 | — | — | WO | disclosed |