Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653935 | 0.89 | CYP1A2 (0.42) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL5762937 | 0.80 | PIN1 (0.49) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL5762947 | 0.80 | KDM4E (0.62) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL4879884 | 0.77 | KDM4E (0.59) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL5820825 | 0.76 | KDM4E (0.66) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL6492450 | 0.76 | TAAR1 (0.62) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL4802255 | 0.76 | SMN1; SMN2 (0.49) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL5759689 | 0.75 | ALDH1A1 (0.69) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL4504351 | 0.74 | MAPK13 (0.59) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL27653936 | 0.73 | KDM4E (0.40) | PIN1CYP1A2MAPK1CASP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | PIN1 735/4885CYP1A2 46/4885MAPK1 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.