Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496395 | 0.84 | PIN1 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12875944 | 0.83 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18003971 | 0.83 | ALDH1A1 (0.58) | L3MBTL1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL12876904 | 0.78 | MAPT (0.54) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL270026 | 0.78 | KDM4E (0.53) | L3MBTL1ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL18003334 | 0.77 | MEN1 (0.44) | L3MBTL1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL29462096 | 0.77 | KDM4E (0.57) | L3MBTL1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18003674 | 0.77 | KDM4E (0.57) | L3MBTL1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18003845 | 0.77 | ALDH1A1 (0.46) | L3MBTL1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL1339928 | 0.77 | KDM4E (0.52) | L3MBTL1MAPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |