SCHEMBL6504147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6500780	0.82	HTT (0.42)	HTTGABRPGABRDGABRA1GABRB1
	SCHEMBL15018003	0.81	ALDH1A1 (0.43)	UHRF1HTTNNMTSMN1; SMN2
	SCHEMBL21632976	0.80	SMN1; SMN2 (0.50)	UHRF1HTTTSHRMAPK1SMN1; SMN2
	SCHEMBL20772268	0.77	HTT (0.41)	HTTGABRPGABRDGABRA1GABRB1
	SCHEMBL14224045	0.77	UHRF1 (0.54)	UHRF1GABRPGABRDGABRA1GABRB1
	SCHEMBL23948608	0.76	UHRF1 (0.52)	UHRF1GABRPGABRDGABRA1GABRB1
	SCHEMBL21666114	0.74	UHRF1 (0.50)	UHRF1GABRPGABRDGABRA1GABRB1
	SCHEMBL31230433	0.74	UHRF1 (0.50)	UHRF1GABRPGABRDGABRA1GABRB1
	Hydrochloric Acid SCHEMBL30756158	0.72	HSD17B10 (0.45)	HTTMAPTTDP1CYP3A4TSHR
	SCHEMBL30595305	0.72	HTT (0.46)	HTTTDP1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.