Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211973 | 1.00 | MEN1 (0.48) | MEN1POLBKMT2AACECA2 | |
| SCHEMBL13868571 | 0.89 | GAA (0.53) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL6048079 | 0.89 | KMT2A (0.47) | MEN1POLBKMT2ACTSGCTRB1 | |
| SCHEMBL29067682 | 0.89 | GAA (0.53) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL4896289 | 0.89 | GAA (0.53) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL5118660 | 0.88 | CA2 (0.49) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL5210394 | 0.88 | CA2 (0.49) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL6507992 | 0.86 | CA2 (0.51) | CA2CA1CTSLGAAALDH1A1 | |
| SCHEMBL5222859 | 0.86 | KMT2A (0.51) | MEN1POLBKMT2ACA2CA1 | |
| SCHEMBL14254899 | 0.84 | HDAC3 (0.52) | MEN1POLBKMT2ACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476742-B2 | Indane acetic acid derivatives and their use as pharmaceutical agents | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-01-13 | — | — | US | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |