Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210394 | 1.00 | CA2 (0.49) | CA2CA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26823872 | 0.88 | TAS1R3 (0.50) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL820939 | 0.88 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL8211973 | 0.88 | MEN1 (0.48) | CA2CA1MEN1KMT2AHPGD | |
| SCHEMBL6504398 | 0.88 | MEN1 (0.48) | CA2CA1MEN1KMT2AHPGD | |
| SCHEMBL6507992 | 0.87 | CA2 (0.51) | CA2CA1HPGDLMNAALDH1A1 | |
| SCHEMBL5222859 | 0.87 | KMT2A (0.51) | CA2CA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29277520 | 0.84 | CA2 (0.62) | CA2CA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12985394 | 0.83 | SMN1; SMN2 (0.50) | CA2CA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12985393 | 0.83 | SMN1; SMN2 (0.50) | CA2CA1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026067-A1 | Method for Increasing Specific Surface Area of Slightly Soluble Drug | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1741704-A1 | METHOD FOR INCREASING SPECIFIC SURFACE AREA OF SLIGHTLY SOLUBLE DRUG | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |