Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506417 | 0.88 | CTSL (0.50) | CA2CTSLALDH1A1HPGDNPC1 | |
| SCHEMBL5118660 | 0.87 | CA2 (0.49) | CA2ALDH1A1HPGDGAACA1 | |
| SCHEMBL5210394 | 0.87 | CA2 (0.49) | CA2ALDH1A1HPGDGAACA1 | |
| SCHEMBL6504398 | 0.86 | MEN1 (0.48) | CA2CTSLALDH1A1HPGDGAA | |
| SCHEMBL8211973 | 0.86 | MEN1 (0.48) | CA2CTSLALDH1A1HPGDGAA | |
| SCHEMBL16447466 | 0.86 | FOLH1 (0.54) | CA2CTSLALDH1A1HPGDNPC1 | |
| SCHEMBL19612083 | 0.86 | FOLH1 (0.54) | CA2CTSLALDH1A1HPGDNPC1 | |
| SCHEMBL5222859 | 0.85 | KMT2A (0.51) | CA2ALDH1A1HPGDCA1LMNA | |
| SCHEMBL16446806 | 0.83 | FOLH1 (0.55) | CA2ALDH1A1HPGDFOLH1 | |
| SCHEMBL16447113 | 0.83 | FOLH1 (0.55) | CA2ALDH1A1HPGDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |