Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL6506783 | 0.95 | HCRTR1 (0.37) | HCRTR1HCRTR2PARP1MTNR1BDRD1 | |
| SCHEMBL6027512 | 0.86 | HCRTR1 (0.41) | HCRTR1HCRTR2PARP1MTNR1BDRD1 | |
| SCHEMBL4418264 | 0.83 | MTNR1B (0.52) | HCRTR1HCRTR2PARP1MTNR1BGRIN2C | |
| SCHEMBL4417027 | 0.83 | MTNR1B (0.47) | HCRTR1HCRTR2PARP1MTNR1BGRIN2C | |
| SCHEMBL4423047 | 0.81 | GRIN2C (0.51) | MTNR1BGRIN2CCA1CA2CA9 | |
| SCHEMBL4552332 | 0.81 | TAS2R14 (0.49) | HCRTR1HCRTR2CA1CA2CA9 | |
| SCHEMBL13972857 | 0.81 | TAS2R14 (0.49) | HCRTR1HCRTR2CA1CA2CA9 | |
| SCHEMBL4416192 | 0.81 | GRIN2C (0.47) | MTNR1BGRIN2CCA1CA2CA9 | |
| SCHEMBL4418256 | 0.81 | KMT2A (0.52) | GRIN2CCA1CA2CA9CA14 | |
| SCHEMBL4413447 | 0.81 | KMT2A (0.55) | GRIN2CCA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070570-A1 | Novel potassium channels modulators | 4SC AG (DE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070570-A1 | Novel potassium channels modulators | HCN4, KCNA4, KCNN4 | HCRTR1 281/4885HCRTR2 218/4885PARP1 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.