Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.97 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.74 |
| ▸ | HTR3B | O95264 | 3/20 | 0.74 |
| ▸ | HTR3A | P46098 | 3/20 | 0.74 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.74 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | MTOR | P42345 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504516 | 1.00 | CYP2D6 (0.97) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL14685717 | 1.00 | CYP2D6 (0.97) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL6500334 | 0.87 | HTR3E (0.76) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL6500328 | 0.87 | HTR3E (0.76) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| Bemesetron SCHEMBL5790539 | 0.85 | CYP2D6 (1.00) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL1851573 | 0.85 | HTR3E (0.74) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL16282624 | 0.85 | HTR3E (0.74) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| SCHEMBL1851576 | 0.85 | HTR3E (0.74) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| Bemesetron SCHEMBL10765684 | 0.85 | CYP2D6 (1.00) | CYP2D6CYP2C19LMNAHTR3EHTR3B | |
| Bemesetron SCHEMBL195148 | 0.85 | CYP2D6 (1.00) | CYP2D6CYP2C19LMNAHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054680-A1 | Agonists and antagonists of 5h3-like receptors of invertebrates as pesticides | COMMONWEALTH SCIENTIFIC INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054680-A1 | Agonists and antagonists of 5h3-like receptors of invertebrates as pesticides | HTR3C, HTR3A, HTR3E | CYP2D6 998/4885CYP2C19 1031/4885LMNA 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.