Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509590 | 0.91 | KDM4E (0.49) | KDM4ESMN1; SMN2MAPTHSD17B10PARP1 | |
| SCHEMBL6505871 | 0.91 | PARP1 (0.45) | KDM4EHSD17B10MAPK1DYRK1APARP1 | |
| SCHEMBL6508473 | 0.85 | MAPK1 (0.46) | KDM4ESMN1; SMN2MAPTHSD17B10MAPK1 | |
| SCHEMBL17731555 | 0.75 | IRAK4 (0.56) | KDM4ESMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL6500237 | 0.73 | KDM4E (0.62) | KDM4ESMN1; SMN2HSD17B10MAPK1LMNA | |
| SCHEMBL6683837 | 0.70 | NPC1 (0.63) | KDM4ESMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL6644132 | 0.69 | RAB9A (0.43) | KDM4EMAPTHSD17B10MAPK1PARP1 | |
| SCHEMBL17554100 | 0.68 | HTT (0.75) | ALDH1A1HTTGAAEPHX2MEN1 | |
| SCHEMBL11711021 | 0.66 | KDM4E (0.73) | KDM4ESMN1; SMN2HSD17B10MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL8814898 | 0.66 | GRIN2B (0.59) | KDM4EHSD17B10TP53MAPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |