Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460781 | 0.90 | LMNA (0.45) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460821 | 0.89 | PPARG (0.46) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460746 | 0.88 | LMNA (0.43) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460901 | 0.88 | RECQL (0.44) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460745 | 0.86 | ROCK2 (0.45) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460786 | 0.86 | HDAC1 (0.46) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13461041 | 0.85 | LMNA (0.46) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460924 | 0.84 | ROCK2 (0.45) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13460741 | 0.84 | LMNA (0.45) | CYP1A2LMNAPOLBRECQLTHRB | |
| SCHEMBL13461038 | 0.82 | FLT1 (0.44) | CYP1A2LMNAPOLBRECQLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |