Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427333 | 0.88 | ALDH1A1 (0.44) | HPGDEPHX1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6390865 | 0.85 | KMT2A (0.46) | HPGDKMT2AEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1605522 | 0.85 | KDM4C (0.38) | KMT2AEPHX1ALDH1A1RECQLMEN1 | |
| SCHEMBL6498171 | 0.83 | EPHX1 (0.40) | HPGDKMT2AEPHX1ALDH1A1LMNA | |
| SCHEMBL6498178 | 0.83 | EPHX1 (0.40) | HPGDKMT2AEPHX1ALDH1A1LMNA | |
| SCHEMBL6427044 | 0.81 | TSHR (0.47) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6427385 | 0.81 | TSHR (0.47) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6503596 | 0.81 | TSHR (0.47) | HPGDKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6428725 | 0.79 | ALDH1A1 (0.59) | HPGDKMT2AEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6393753 | 0.79 | SLC6A2 (0.35) | ALDH1A1LMNARECQLPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | HPGD 66/4885KMT2A 3213/4885EPHX1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.