Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428140 | 1.00 | KMT2A (0.50) | KMT2AMEN1ALDH1A1GAARECQL | |
| SCHEMBL6428130 | 0.87 | KMT2A (0.49) | KMT2AMEN1ALDH1A1GAARECQL | |
| SCHEMBL6502742 | 0.83 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL6425891 | 0.83 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL6427136 | 0.83 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL6501368 | 0.83 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL6429260 | 0.83 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL6392819 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6507694 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL6427850 | 0.81 | TSHR (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | KMT2A 3213/4885MEN1 979/4885ALDH1A1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.