Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428776 | 0.82 | ALDH1A1 (0.49) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6427907 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL6499328 | 0.82 | ALDH1A1 (0.50) | TAAR1ACEMEN1KMT2AALDH1A1 | |
| SCHEMBL6508183 | 0.82 | ALDH1A1 (0.50) | TAAR1ACEMEN1KMT2AALDH1A1 | |
| SCHEMBL6393517 | 0.81 | ALDH1A1 (0.55) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6427188 | 0.80 | ALDH1A1 (0.57) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6426510 | 0.80 | ALDH1A1 (0.57) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6510576 | 0.77 | DPP4 (0.52) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6430684 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6427337 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | TAAR1 1806/4885ACE 449/4885MEN1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.