SCHEMBL6504791

SCHEMBL6504791

CC(O[Si](C)(C)C)(C1CC2C=CC1C2)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366163 0.81 ALDH1A1 (0.32) USP2ALDH1A1TDP1
SCHEMBL3364848 0.74 KDM4E (0.37) USP2ALDH1A1TDP1
SCHEMBL13532353 0.72 ALDH1A1 (0.35) USP2ALDH1A1TDP1
SCHEMBL3365779 0.72 KDM4E (0.32) USP2ALDH1A1TDP1
SCHEMBL13259999 0.72 ALDH1A1 (0.36) USP2ALDH1A1TDP1
SCHEMBL6506156 0.70
SCHEMBL119840 0.69 ALDH1A1 (0.39) USP2ALDH1A1TDP1
SCHEMBL11921079 0.69 ALDH1A1 (0.35) USP2ALDH1A1TDP1
SCHEMBL444687 0.68 USP2 (0.30) USP2ALDH1A1TDP1
SCHEMBL4387300 0.68 USP2 (0.33) USP2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949615-B2 Monomer having electron-withdrawing group and process for preparing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-27 US disclosed