Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633897 | 0.87 | KDM4E (0.57) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL4925692 | 0.83 | TP53 (0.52) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5096428 | 0.81 | ALDH1A1 (0.51) | KDM4ESMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL5093853 | 0.81 | TARBP2 (0.54) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5762006 | 0.81 | HSD17B10 (0.56) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL4037331 | 0.80 | KDM4E (0.69) | KDM4EHPGDRAB9ALMNANPC1 | |
| SCHEMBL6511253 | 0.79 | KDM4E (0.60) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL5385072 | 0.79 | KDM4E (0.50) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL17778918 | 0.78 | SMN1; SMN2 (0.71) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL12006897 | 0.78 | SMN1; SMN2 (0.71) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |