Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504901 | 0.87 | KDM4E (0.55) | KDM4ESMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL13503414 | 0.84 | TARBP2 (0.53) | KDM4ESMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL12961041 | 0.81 | ALDH1A1 (0.52) | KDM4EMAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL9097470 | 0.81 | ESR1 (0.50) | KDM4ESMN1; SMN2MAPTRAB9AHSD17B10 | |
| SCHEMBL13179907 | 0.81 | HSD17B10 (0.58) | KDM4ESMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL18966853 | 0.81 | RAB9A (0.46) | KDM4ESMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL266619 | 0.81 | KDM4E (0.66) | KDM4ERAB9AHPGDLMNAMEN1 | |
| SCHEMBL13638657 | 0.79 | KDM4E (0.50) | KDM4ESMN1; SMN2MAPTRAB9AALDH1A1 | |
| SCHEMBL12006897 | 0.78 | SMN1; SMN2 (0.71) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL17778918 | 0.78 | SMN1; SMN2 (0.71) | KDM4ESMN1; SMN2MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | CADILA HEALTHCARE LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | UGT1A7, UGT1A10, UGT2B7 | KDM4E 4614/4885SMN1; SMN2 2873/4885MAPT 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.