Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125825 | 0.82 | POLB (0.55) | CYP1A2POLBCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL8253548 | 0.82 | POLB (0.55) | CYP1A2POLBCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL6321928 | 0.82 | POLB (0.55) | CYP1A2POLBCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL5158011 | 0.80 | HSD11B1 (0.51) | HSD11B1HSD17B10L3MBTL1EPHX2MEN1 | |
| SCHEMBL24441127 | 0.80 | POLB (0.58) | CYP1A2POLBCYP3A4CYP2C19HSD11B1 | |
| SCHEMBL29044252 | 0.80 | POLB (0.58) | CYP1A2POLBCYP3A4CYP2C19HSD11B1 | |
| SCHEMBL29044251 | 0.80 | POLB (0.58) | CYP1A2POLBCYP3A4CYP2C19HSD11B1 | |
| SCHEMBL3333984 | 0.80 | POLB (0.53) | CYP1A2POLBCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL957407 | 0.80 | POLB (0.53) | CYP1A2POLBCYP3A4CYP2C19HSD17B10 | |
| SCHEMBL8907775 | 0.79 | POLB (0.57) | CYP1A2POLBCYP3A4CYP2C19HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261290-A1 | Novel compounds of proline and morpholine derivatives | CHENG HENGMIAO | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261290-A1 | Novel compounds of proline and morpholine derivatives | CYP11B1, HSD11B1, CYP11B2 | CYP1A2 67/4885POLB 2231/4885CYP3A4 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.