Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 9/20 | 0.57 |
| ▸ | MMP13 | P45452 | 3/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369009 | 0.88 | MMP12 (0.58) | MMP12NR1H4MEN1TP53KMT2A | |
| SCHEMBL6368918 | 0.87 | MMP12 (0.74) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6369477 | 0.87 | MMP12 (0.74) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8301127 | 0.77 | MMP12 (0.57) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6367846 | 0.76 | MMP12 (0.76) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL8300063 | 0.76 | MMP12 (0.76) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6451843 | 0.74 | POLB (0.60) | MMP12MMP13NR1H4MMP8MEN1 | |
| SCHEMBL6455132 | 0.74 | NR1H4 (0.64) | MMP12NR1H4MEN1TP53KMT2A | |
| SCHEMBL6456631 | 0.74 | MMP12 (0.57) | MMP12NR1H4MEN1TP53KMT2A | |
| SCHEMBL6367844 | 0.72 | MMP12 (0.51) | MMP12MMP13MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003115-A1 | THIOPHENE AMINO ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-13 | — | — | WO | claimed |