SCHEMBL6505199

SCHEMBL6505199

COc1cc(-c2ccc(C(=N)NO)cc2)cc(-c2nc3cc(C(N)=NO)ccc3[nH]2)c1O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.46
F2 P00734 10/20 0.46
PLG P00747 10/20 0.46
PLAU P00749 10/20 0.46
PLAT P00750 10/20 0.46
PRSS1 P07477 6/20 0.46
HDAC6 Q9UBN7 2/20 0.45
AMY1A P0DUB6 2/20 0.38
KLKB1 P03952 2/20 0.37
F7 P08709 2/20 0.37
CHEK2 O96017 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6505174 0.91 HDAC6 (0.46) F10F2PLGPLAUPLAT
SCHEMBL6511666 0.90 HDAC6 (0.42) F10F2PLGPLAUPLAT
SCHEMBL6510692 0.84 F2 (0.47) F10F2PLGPLAUPLAT
SCHEMBL5392746 0.83 F10 (0.60) F10F2PLGPLAUPLAT
SCHEMBL6530669 0.83 HDAC6 (0.40) F10F2PLGPLAUPLAT
SCHEMBL6510570 0.82 F2 (0.55) F10F2PLGPLAUPLAT
SCHEMBL6511656 0.80 AMY1A (0.42) F10F2PLGPLAUPLAT
SCHEMBL6505463 0.80 HDAC6 (0.45) F10F2PLGPLAUPLAT
Acetic Acid SCHEMBL6062185 0.79 F2 (0.55) F10F2PLGPLAUPLAT
SCHEMBL6506693 0.78 HDAC1 (0.48) F10F2PLAUPRSS1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050148646-A1 Dicationic triaryl analogs as anti-protozoan agents BOYKIN DAVID W (US) 2005-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148646-A1 Dicationic triaryl analogs as anti-protozoan agents DDT, DDC, DARS1 F10 3872/4885F2 2666/4885PLG 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.