Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504044 | 0.80 | CTSV (0.48) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL6496527 | 0.78 | CTSV (0.51) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL6498712 | 0.77 | MAOA (0.52) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL6505220 | 0.75 | CTSV (0.47) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL22541444 | 0.74 | CHEK1 (0.56) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL6494988 | 0.73 | MAOA (0.48) | MAOAMAOBCTSVCTSLCHEK1 | |
| SCHEMBL28367519 | 0.71 | TRPM8 (0.53) | MAOAMAOBCTSVCTSLNSD2 | |
| SCHEMBL16072720 | 0.70 | KCNA3 (0.58) | MAOB | |
| SCHEMBL15536042 | 0.69 | CTSV (0.69) | MAOAMAOBCTSVCTSLNSD2 | |
| SCHEMBL22628995 | 0.69 | CTSV (0.54) | MAOAMAOBCTSVCTSLNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844445-B2 | Indenoindolone compounds | LES LABORATOIRES SERVIER (FR) | 2005-01-18 | — | — | US | disclosed |