SCHEMBL6505295

SCHEMBL6505295

CCCCc1cc([C]=O)no1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.43
RAB9A P51151 7/20 0.35
HPGD P15428 1/20 0.35
NPC1 O15118 5/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
XBP1 P17861 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TLR8 Q9NR97 1/20 0.33
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091123 0.93 PPARA (0.51) PPARARAB9AHPGDNPC1SMN1; SMN2
SCHEMBL6511731 0.89 RAB9A (0.43) RAB9AHPGDNPC1SMN1; SMN2S1PR1
SCHEMBL6507665 0.81
SCHEMBL13991120 0.76 PPARA (0.54) PPARARAB9ANPC1SMN1; SMN2S1PR1
SCHEMBL10262683 0.73 MEN1 (0.44) PPARARAB9AHPGDNPC1SMN1; SMN2
SCHEMBL1128893 0.73 ALDH1A1 (0.43) RAB9AHPGDNPC1SMN1; SMN2S1PR1
SCHEMBL1758968 0.72 PPARA (0.43) PPARARAB9AHPGDNPC1SMN1; SMN2
SCHEMBL10469531 0.72 PPARA (0.46) PPARARAB9AHPGDNPC1SMN1; SMN2
SCHEMBL4030288 0.71 SMN1; SMN2 (0.50) PPARARAB9AHPGDNPC1SMN1; SMN2
SCHEMBL11721077 0.71 PPARA (0.54) PPARARAB9AHPGDNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082892-A2 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2005-09-09 WO disclosed